Banse et al. (2024). Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes.eLife.
DOI:10.7554/eLife.104375
Banse et al. (2024). Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain-specific lifespan and health effects in Caenorhabditis nematodes.GeroScience.
DOI:10.1007/s11357-023-00978-0PMID:37923874
Onken et al. (2021). Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes.Aging Cell.
DOI:10.1111/acel.13488PMID:34837316
Banse et al. (2019). Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions.GeroScience.
DOI:10.1007/s11357-019-00108-9PMID:31820364
Lucanic et al. (2017). Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects.Nature Communications.
DOI:10.1038/ncomms14256PMID:28220799
Banse et al. (2025). Caenorhabditis Intervention Testing Program: all-trans retinoic acid-related compounds tamibarotene and bakuchiol do not extend lifespan in Caenorhabditis nematodes.microPublication Biology.
DOI:10.17912/micropub.biology.001517PMID:40027526
Osman et al. (2021). Caenorhabditis Intervention Testing Program: the herbicide diuron does not robustly extend lifespan in nematodes.microPublication Biology.
DOI:10.17912/micropub.biology.000448PMID:34585102
Morshead et al. (2020). Caenorhabditis Intervention Testing Program: the farnesoid X receptor agonist obeticholic acid does not robustly extend lifespan in nematodes.microPublication Biology.
DOI:10.17912/micropub.biology.000257PMID:32550518
Coleman-Hulbert et al. (2020). Caenorhabditis Intervention Testing Program: the creatine analog β-guanidinopropionic acid does not extend lifespan in nematodes.microPublication Biology.
DOI:10.17912/micropub.biology.000207PMID:31998863
Coleman-Hulbert et al. (2019). Caenorhabditis Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes.microPublication Biology.
DOI:10.17912/micropub.biology.000131PMID:32010883
Acknowledging the CITP in your publications will help us maintain our funding. Please use the following statement in any publications in which you used data obtained from the CITP, including the grant numbers: "Some data were downloaded from the CITP Data Portal (citpaging.org), which is supported by funding from NIH's NIA Division of Aging Biology grants (U01 AG045844, U01 AG045864, U01 AG045829, and U24 AG056052)."
Caenorhabditis Intervention Testing Program Data Portal Version 2.1
The Data Portal provides access to lifespan and transcriptomics data published by the Caenorhabditis Intervention Testing Program (CITP).
Click the Browse button next to each publication on the Portal home page to access specific data and analytical summaries.
You can access lifespan data download files grouped by dataset, compound, and/or worm strain. Downloads are available in comma-separated value CSV and Excel XLSX formats. Click below to retrieve all CITP lifespan data published to date:
The fields/columns in the lifespan download files are described in the data dictionary:
Dataset, compound, and strain metadata can be obtained by clicking the Export button at the top of the table on each page.
You can browse lifespan summary statistics and Kaplan–Meier survival plots by dataset, compound, and strain. RNA-seq differential gene expression tables and plots are available from more recent studies. These analytical summaries can be downloaded by clicking the Export button at the top of each table.
Please refer to the relevant publications for details about lifespan and RNA-seq analytical methods.